Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

Hormone sensitive lipase (HSL) regulates the hydrolysis of acylglycerols and cholesteryl esters (CE) in various cells and organs, including enterocytes of the small intestine. The physiological role of this enzyme in enterocytes, however, stayed elusive. In the present study we generated mice lackin...

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Main Authors: Obrowsky, Sascha, Chandak, Prakash G., Patankar, Jay V., Pfeifer, Thomas, Povoden, Silvia, Schreiber, Renate, Haemmerle, Guenter, Levak-Frank, Sanja, Kratky, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Pub. Co 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459056/
https://ncbi.nlm.nih.gov/pubmed/22842588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.07.013
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