Reactive oxygen species contribute to the development of arrhythmogenic Ca(2+) waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes

While β-adrenergic receptor (β-AR) stimulation leads to positive inotropic effects, it can also induce arrhythmogenic Ca(2+) waves. β-AR stimulation increases mitochondrial oxygen consumption and, thereby, the production of reactive oxygen species (ROS). We therefore investigated the role of ROS in...

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Bibliografiska uppgifter
Huvudupphovsmän: Bovo, Elisa, Lipsius, Stephen L, Zima, Aleksey V
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2012
Ämnen:
Cardiovascular
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459043/
https://ncbi.nlm.nih.gov/pubmed/22586224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.230748
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