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Reactive oxygen species contribute to the development of arrhythmogenic Ca(2+) waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes
While β-adrenergic receptor (β-AR) stimulation leads to positive inotropic effects, it can also induce arrhythmogenic Ca(2+) waves. β-AR stimulation increases mitochondrial oxygen consumption and, thereby, the production of reactive oxygen species (ROS). We therefore investigated the role of ROS in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459043/ https://ncbi.nlm.nih.gov/pubmed/22586224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.230748 |
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