Expression of a cloned adenovirus gene is inhibited by in vitro methylation.

In many viral and nonviral eukaryotic systems, an inverse correlation has been observed between the extent of DNA methylation at 5'-C-C-G-G-3' sites and the extent of expression of specific genes as mRNA. The E2a region of adenovirus serotype 2 (Ad2) DNA encodes the Ad2-specific DNA binding protein...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Vardimon, L, Kressmann, A, Cedar, H, Maechler, M, Doerfler, W
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1982
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345902/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6951163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.4.1073
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