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Expression of a cloned adenovirus gene is inhibited by in vitro methylation.

In many viral and nonviral eukaryotic systems, an inverse correlation has been observed between the extent of DNA methylation at 5'-C-C-G-G-3' sites and the extent of expression of specific genes as mRNA. The E2a region of adenovirus serotype 2 (Ad2) DNA encodes the Ad2-specific DNA bindin...

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Main Authors: Vardimon, L, Kressmann, A, Cedar, H, Maechler, M, Doerfler, W
格式: Artigo
語言:Inglês
出版: 1982
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC345902/
https://ncbi.nlm.nih.gov/pubmed/6951163
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