IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis

Studies in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, have shown that B cells markedly influence the course of the disease, although whether their effects are protective or pathological is a matter of debate. EndoS hydrolysis of the IgG glycan has profound...

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Bibliographic Details
Main Authors: Benkhoucha, Mahdia, Molnarfi, Nicolas, Santiago-Raber, Marie-Laure, Weber, Martin S, Merkler, Doron, Collin, Mattias, Lalive, Patrice H
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458989/
https://ncbi.nlm.nih.gov/pubmed/22943418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-209
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