NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development

A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was to study the functional role of NOX4 in different cell populations implicated in liver fibrosis: hepatic stellate cells (HSC), myofibroblats...

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Hauptverfasser: Sancho, Patricia, Mainez, Jèssica, Crosas-Molist, Eva, Roncero, César, Fernández-Rodriguez, Conrado M., Pinedo, Fernando, Huber, Heidemarie, Eferl, Robert, Mikulits, Wolfgang, Fabregat, Isabel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458844/
https://ncbi.nlm.nih.gov/pubmed/23049784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045285
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