The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination

Epithelial to mesenchymal transition is a common event during tumour dissemination. However, direct epithelial to amoeboid transition has not been characterized to date. Here we provide evidence that cells from hepatocellular carcinoma (HCC), a highly metastatic cancer, undergo epithelial to amoeboi...

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Detalhes bibliográficos
Publicado no:Oncogene
Principais autores: Crosas-Molist, E, Bertran, E, Rodriguez-Hernandez, I, Herraiz, C, Cantelli, G, Fabra, À, Sanz-Moreno, V, Fabregat, I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354266/
https://ncbi.nlm.nih.gov/pubmed/27941881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.454
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