TGF-β dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells

BACKGROUND: The activation of hepatic stellate cells (HSCs) plays a pivotal role during liver injury because the resulting myofibroblasts (MFBs) are mainly responsible for connective tissue re-assembly. MFBs represent therefore cellular targets for anti-fibrotic therapy. In this study, we employed a...

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Detalhes bibliográficos
Main Authors: Proell, Verena, Carmona-Cuenca, Irene, Murillo, Miguel M, Huber, Heidemarie, Fabregat, Isabel, Mikulits, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804283/
https://ncbi.nlm.nih.gov/pubmed/17311678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-6-1
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