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Dynamics of CRISPR/Cas9-mediated genomic editing of the AXL locus in hepatocellular carcinoma cells

Genomic editing using the CRISPR/Cas9 technology allows selective interference with gene expression. With this method, a multitude of haploid and diploid cells from different organisms have been employed to successfully generate knockouts of genes coding for proteins or small RNAs. Yet, cancer cells...

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Detalles Bibliográficos
Publicado en:Oncol Lett
Main Authors: Scharf, Irene, Bierbaumer, Lisa, Huber, Heidemarie, Wittmann, Philipp, Haider, Christine, Pirker, Christine, Berger, Walter, Mikulits, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777348/
https://ncbi.nlm.nih.gov/pubmed/29434956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7605
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