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NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells through Up-regulation of the Epidermal Growth Factor Receptor Pathway

FaO rat hepatoma cells proliferate in the absence of serum through a mechanism that requires activation of the epidermal growth factor receptor (EGFR) pathway. The aim of this work was to analyze the molecular mechanisms that control EGFR activation in these and other liver tumor cells. Reactive oxy...

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Detalhes bibliográficos
Main Authors: Sancho, Patricia, Fabregat, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915717/
https://ncbi.nlm.nih.gov/pubmed/20525691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114280
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