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NADPH Oxidase NOX1 Controls Autocrine Growth of Liver Tumor Cells through Up-regulation of the Epidermal Growth Factor Receptor Pathway

FaO rat hepatoma cells proliferate in the absence of serum through a mechanism that requires activation of the epidermal growth factor receptor (EGFR) pathway. The aim of this work was to analyze the molecular mechanisms that control EGFR activation in these and other liver tumor cells. Reactive oxy...

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Bibliografiske detaljer
Main Authors: Sancho, Patricia, Fabregat, Isabel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915717/
https://ncbi.nlm.nih.gov/pubmed/20525691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114280
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