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On the proposed structures and stereocontrolled synthesis of the cephalosporolides

The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a zinc-chelation strategy for controlling the stereochemistry of oxygenated 5,5-spiroketals. The same strategy likewise enables the first stereocontrolled synthesis of cephalosporolide E, which is typi...

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Bibliografiska uppgifter
Huvudupphovsmän: Tlais, Sami F, Dudley, Gregory B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Beilstein-Institut 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458751/
https://ncbi.nlm.nih.gov/pubmed/23019461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.146
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