Tetraploid State Induces p53-dependent Arrest of Nontransformed Mammalian Cells in G1

A “spindle assembly” checkpoint has been described that arrests cells in G1 following inappropriate exit from mitosis in the presence of microtubule inhibitors. We have here addressed the question of whether the resulting tetraploid state itself, rather than failure of spindle function or induction...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Andreassen, Paul R., Lohez, Olivier D., Lacroix, Françoise B., Margolis, Robert L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.5.1315
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