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Intracellular interleukin 6 mediates platelet-derived growth factor-induced proliferation of nontransformed cells.

The functional relevance of interleukin 6 (IL-6) in platelet-derived growth factor (PDGF)-induced cell growth was evaluated in cultures of human fibroblasts, vascular smooth muscle cells, and mesangial cells. The three isoforms of the PDGF--namely, PDGF-AA, -AB, and -BB--induced the expression of th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Roth, M, Nauck, M, Tamm, M, Perruchoud, A P, Ziesche, R, Block, L H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7877973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1312
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