Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

Cytokines are thought to be important mediators in physiologic and pathophysiologic processes affecting the central nervous system (CNS). To explore this hypothesis, transgenic mice were generated in which the cytokine interleukin 6 (IL-6), under the regulatory control of the glial fibrillary acidic...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Campbell, I L, Abraham, C R, Masliah, E, Kemper, P, Inglis, J D, Oldstone, M B, Mucke, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47713/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7694279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10061
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