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Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.

Cytokines are thought to be important mediators in physiologic and pathophysiologic processes affecting the central nervous system (CNS). To explore this hypothesis, transgenic mice were generated in which the cytokine interleukin 6 (IL-6), under the regulatory control of the glial fibrillary acidic...

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Detalhes bibliográficos
Main Authors: Campbell, I L, Abraham, C R, Masliah, E, Kemper, P, Inglis, J D, Oldstone, M B, Mucke, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47713/
https://ncbi.nlm.nih.gov/pubmed/7694279
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