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p21 promotes error-free replication-coupled DNA double-strand break repair
p21 is a well-established regulator of cell cycle progression. The role of p21 in DNA repair, however, remains poorly characterized. Here, we describe a critical role of p21 in a replication-coupled DNA double-strand break (DSB) repair that is mechanistically distinct from its cell cycle checkpoint...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458556/ https://ncbi.nlm.nih.gov/pubmed/22735704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks612 |
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