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Modular control of multiple pathways using engineered orthogonal T7 polymerases

Synthetic genetic sensors and circuits enable programmable control over the timing and conditions of gene expression. They are being increasingly incorporated into the control of complex, multigene pathways and cellular functions. Here, we propose a design strategy to genetically separate the sensin...

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Autors principals: Temme, Karsten, Hill, Rena, Segall-Shapiro, Thomas H., Moser, Felix, Voigt, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458549/
https://ncbi.nlm.nih.gov/pubmed/22743271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks597
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