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A ‘resource allocator’ for transcription based on a highly fragmented T7 RNA polymerase

Synthetic genetic systems share resources with the host, including machinery for transcription and translation. Phage RNA polymerases (RNAPs) decouple transcription from the host and generate high expression. However, they can exhibit toxicity and lack accessory proteins (σ factors and activators) t...

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Detalles Bibliográficos
Publicado en:Mol Syst Biol
Main Authors: Segall-Shapiro, Thomas H, Meyer, Adam J, Ellington, Andrew D, Sontag, Eduardo D, Voigt, Christopher A
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299498/
https://ncbi.nlm.nih.gov/pubmed/25080493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145299
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