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Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme.

The T7 RNA polymerase-T7 lysozyme complex regulates phage gene expression during infection of Escherichia coli. The 2.8 A crystal structure of the complex reveals that lysozyme binds at a site remote from the polymerase active site, suggesting an indirect mechanism of inhibition. Comparison of the T...

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Detalhes bibliográficos
Main Authors: Jeruzalmi, D, Steitz, T A
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170743/
https://ncbi.nlm.nih.gov/pubmed/9670025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.14.4101
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