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The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson, RAPADILINO and Baller–Gerold syndromes. Mouse models and experiments in human and Xenopus have proven the N-terminal part of RecQL4 to be vital f...

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Bibliografske podrobnosti
Main Authors: Ohlenschläger, Oliver, Kuhnert, Anja, Schneider, Annerose, Haumann, Sebastian, Bellstedt, Peter, Keller, Heidi, Saluz, Hans-Peter, Hortschansky, Peter, Hänel, Frank, Grosse, Frank, Görlach, Matthias, Pospiech, Helmut
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458545/
https://ncbi.nlm.nih.gov/pubmed/22730300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks591
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