The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding

Human RecQL4 belongs to the ubiquitous RecQ helicase family. Its N-terminal region represents the only homologue of the essential DNA replication initiation factor Sld2 of Saccharomyces cerevisiae, and also participates in the vertebrate initiation of DNA replication. Here, we utilized a random scre...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Keller, Heidi, Kiosze, Kristin, Sachsenweger, Juliane, Haumann, Sebastian, Ohlenschläger, Oliver, Nuutinen, Tarmo, Syväoja, Juhani E., Görlach, Matthias, Grosse, Frank, Pospiech, Helmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Genome Integrity, Repair and Replication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227796/
https://ncbi.nlm.nih.gov/pubmed/25336622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku993
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