The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson, RAPADILINO and Baller–Gerold syndromes. Mouse models and experiments in human and Xenopus have proven the N-terminal part of RecQL4 to be vital f...

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Detalhes bibliográficos
Main Authors: Ohlenschläger, Oliver, Kuhnert, Anja, Schneider, Annerose, Haumann, Sebastian, Bellstedt, Peter, Keller, Heidi, Saluz, Hans-Peter, Hortschansky, Peter, Hänel, Frank, Grosse, Frank, Görlach, Matthias, Pospiech, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458545/
https://ncbi.nlm.nih.gov/pubmed/22730300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks591
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