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The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson, RAPADILINO and Baller–Gerold syndromes. Mouse models and experiments in human and Xenopus have proven the N-terminal part of RecQL4 to be vital f...

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Dettagli Bibliografici
Autori principali: Ohlenschläger, Oliver, Kuhnert, Anja, Schneider, Annerose, Haumann, Sebastian, Bellstedt, Peter, Keller, Heidi, Saluz, Hans-Peter, Hortschansky, Peter, Hänel, Frank, Grosse, Frank, Görlach, Matthias, Pospiech, Helmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458545/
https://ncbi.nlm.nih.gov/pubmed/22730300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks591
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