Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

The presence of growth-induced solid stresses in tumors has been suspected for some time, but these stresses were largely estimated using mathematical models. Solid stresses can deform the surrounding tissues and compress intratumoral lymphatic and blood vessels. Compression of lymphatic vessels ele...

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Detalhes bibliográficos
Main Authors: Stylianopoulos, Triantafyllos, Martin, John D., Chauhan, Vikash P., Jain, Saloni R., Diop-Frimpong, Benjamin, Bardeesy, Nabeel, Smith, Barbara L., Ferrone, Cristina R., Hornicek, Francis J., Boucher, Yves, Munn, Lance L., Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458380/
https://ncbi.nlm.nih.gov/pubmed/22932871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213353109
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