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Diffusion Anisotropy in Collagen Gels and Tumors: The Effect of Fiber Network Orientation

The interstitial matrix is comprised of cross-linked collagen fibers, generally arranged in nonisotropic orientations. Spatial alignment of matrix components within the tissue can affect diffusion patterns of drugs. In this study, we developed a methodology for the calculation of diffusion coefficie...

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Bibliografiske detaljer
Main Authors: Stylianopoulos, Triantafyllos, Diop-Frimpong, Benjamin, Munn, Lance L., Jain, Rakesh K.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980743/
https://ncbi.nlm.nih.gov/pubmed/21081058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.065
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