Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

The presence of growth-induced solid stresses in tumors has been suspected for some time, but these stresses were largely estimated using mathematical models. Solid stresses can deform the surrounding tissues and compress intratumoral lymphatic and blood vessels. Compression of lymphatic vessels ele...

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Bibliographic Details
Main Authors: Stylianopoulos, Triantafyllos, Martin, John D., Chauhan, Vikash P., Jain, Saloni R., Diop-Frimpong, Benjamin, Bardeesy, Nabeel, Smith, Barbara L., Ferrone, Cristina R., Hornicek, Francis J., Boucher, Yves, Munn, Lance L., Jain, Rakesh K.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458380/
https://ncbi.nlm.nih.gov/pubmed/22932871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213353109
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