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Precursor-centric genome-mining approach for lasso peptide discovery

Lasso peptides are a class of ribosomally synthesized posttranslationally modified natural products found in bacteria. Currently known lasso peptides have a diverse set of pharmacologically relevant activities, including inhibition of bacterial growth, receptor antagonism, and enzyme inhibition. The...

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Detalhes bibliográficos
Main Authors: Maksimov, Mikhail O., Pelczer, István, Link, A. James
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458324/
https://ncbi.nlm.nih.gov/pubmed/22949633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208978109
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