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Precursor-centric genome-mining approach for lasso peptide discovery
Lasso peptides are a class of ribosomally synthesized posttranslationally modified natural products found in bacteria. Currently known lasso peptides have a diverse set of pharmacologically relevant activities, including inhibition of bacterial growth, receptor antagonism, and enzyme inhibition. The...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458324/ https://ncbi.nlm.nih.gov/pubmed/22949633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208978109 |
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