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Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase

Lasso peptide isopeptidase is an enzyme that specifically hydrolyzes the isopeptide bond of lasso peptides, rendering these peptides linear. To carry out a detailed structure-activity analysis of the lasso peptide isopeptidase AtxE2 from Asticcacaulis excentricus, we solved NMR structures of its sub...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Maksimov, Mikhail O., Koos, Joseph D., Zong, Chuhan, Lisko, Bozhena, Link, A. James
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692210/
https://ncbi.nlm.nih.gov/pubmed/26534965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.694083
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