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Discovery and structure of the antimicrobial lasso peptide citrocin

We report the identification of citrocin, a 19-amino acid-long antimicrobial lasso peptide from the bacteria Citrobacter pasteurii and Citrobacter braakii. We refactored the citrocin gene cluster and heterologously expressed it in Escherichia coli. We determined citrocin's NMR structure in wate...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Cheung-Lee, Wai Ling, Parry, Madison E., Jaramillo Cartagena, Alexis, Darst, Seth A., Link, A. James
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497930/
https://ncbi.nlm.nih.gov/pubmed/30846564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006494
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