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Direct observation of hydrogen atom dynamics and interactions by ultrahigh resolution neutron protein crystallography

The 1.1 Å, ultrahigh resolution neutron structure of hydrogen/deuterium (H/D) exchanged crambin is reported. Two hundred ninety-nine out of 315, or 94.9%, of the hydrogen atom positions in the protein have been experimentally derived and resolved through nuclear density maps. A number of unconventio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Julian C.-H., Hanson, B. Leif, Fisher, S. Zoë, Langan, Paul, Kovalevsky, Andrey Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458323/
https://ncbi.nlm.nih.gov/pubmed/22949690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208341109
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