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GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1

The ROCO proteins are a family of large, multidomain proteins characterised by the presence of a Ras of complex proteins (ROC) domain followed by a COR, or C-terminal of ROC, domain. It has previously been shown that the ROC domain of the human ROCO protein Leucine Rich Repeat Kinase 2 (LRRK2) contr...

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Detalhes bibliográficos
Main Authors: Jebelli, Joseph D., Dihanich, Sybille, Civiero, Laura, Manzoni, Claudia, Greggio, Elisa, Lewis, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458246/
https://ncbi.nlm.nih.gov/pubmed/23019516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00695
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