Intracellular Trafficking of Clostridium perfringens Iota-Toxin b

Clostridium perfringens iota-toxin is composed of an enzymatic component (Ia) and a binding component (Ib). Ib binds to a cell surface receptor, undergoes oligomerization in lipid rafts, and binds Ia. The resulting complex is then endocytosed. Here, we show the intracellular trafficking of iota-toxi...

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Bibliographische Detailangaben
Hauptverfasser: Nagahama, Masahiro, Umezaki, Mariko, Tashiro, Ryo, Oda, Masataka, Kobayashi, Keiko, Shibutani, Masahiro, Takagishi, Teruhisa, Ishidoh, Kazumi, Fukuda, Mitsunori, Sakurai, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Molecular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457585/
https://ncbi.nlm.nih.gov/pubmed/22825447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00483-12
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