Clostridium perfringens Iota-Toxin b Induces Rapid Cell Necrosis

Clostridium perfringens iota-toxin is a binary toxin composed of an enzyme component (Ia) and a binding component (Ib). Each component alone lacks toxic activity, but together they produce cytotoxic effects. We examined the cytotoxicity of iota-toxin Ib in eight cell lines. A431 and A549 cells were...

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Bibliografiske detaljer
Main Authors: Nagahama, Masahiro, Umezaki, Mariko, Oda, Masataka, Kobayashi, Keiko, Tone, Shigenobu, Suda, Taiji, Ishidoh, Kazumi, Sakurai, Jun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257925/
https://ncbi.nlm.nih.gov/pubmed/21911469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05677-11
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