Binding and Internalization of Clostridium perfringens Iota-Toxin in Lipid Rafts

Clostridium perfringens iota-toxin is a binary toxin composed of an enzymatic component (Ia) and a binding component (Ib). The oligomer of Ib formed in membranes induces endocytosis. We examined the binding and internalization of Ib by using Cy3-labeled Ib. Labeled Ib was retained at the membranes o...

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Bibliografiske detaljer
Main Authors: Nagahama, Masahiro, Yamaguchi, Akiwo, Hagiyama, Tohko, Ohkubo, Noriko, Kobayashi, Keiko, Sakurai, Jun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC415663/
https://ncbi.nlm.nih.gov/pubmed/15155629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3267-3275.2004
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