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Clostridium perfringens Iota-Toxin: Structure and Function

Clostridium perfringens iota-toxin is composed of the enzyme component (Ia) and the binding component (Ib). Ib binds to receptor on targeted cells and translocates Ia into the cytosol of the cells. Ia ADP-ribosylates actin, resulting in cell rounding and death. Comparisons of the deduced amino acid...

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Detalhes bibliográficos
Main Authors: Sakurai, Jun, Nagahama, Masahiro, Oda, Masataka, Tsuge, Hideaki, Kobayashi, Keiko
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202787/
https://ncbi.nlm.nih.gov/pubmed/22069542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins1020208
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