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Clostridium perfringens Iota-Toxin: Structure and Function

Clostridium perfringens iota-toxin is composed of the enzyme component (Ia) and the binding component (Ib). Ib binds to receptor on targeted cells and translocates Ia into the cytosol of the cells. Ia ADP-ribosylates actin, resulting in cell rounding and death. Comparisons of the deduced amino acid...

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Autors principals: Sakurai, Jun, Nagahama, Masahiro, Oda, Masataka, Tsuge, Hideaki, Kobayashi, Keiko
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202787/
https://ncbi.nlm.nih.gov/pubmed/22069542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins1020208
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