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Comparison of Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Solithromycin (CEM-101) in Healthy Adult Subjects

The steady-state concentrations of solithromycin in plasma were compared with concomitant concentrations in epithelial lining fluid (ELF) and alveolar macrophages (AM) obtained from intrapulmonary samples during bronchoscopy and bronchoalveolar lavage (BAL) in 30 healthy adult subjects. Subjects rec...

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Autors principals: Rodvold, Keith A., Gotfried, Mark H., Still, J. Gordon, Clark, Kay, Fernandes, Prabhavathi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457395/
https://ncbi.nlm.nih.gov/pubmed/22802254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00766-12
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