In Vitro and In Vivo Activity of Solithromycin (CEM-101) against Plasmodium Species

With the emergence of Plasmodium falciparum infections exhibiting increased parasite clearance times in response to treatment with artemisinin-based combination therapies, the need for new therapeutic agents is urgent. Solithromycin, a potent new fluoroketolide currently in development, has been sho...

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Detalhes bibliográficos
Main Authors: Wittlin, Sergio, Ekland, Eric, Craft, J Carl, Lotharius, Julie, Bathurst, Ian, Fidock, David A., Fernandes, Prabhavathi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264280/
https://ncbi.nlm.nih.gov/pubmed/22083475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05039-11
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