Comparison of Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Solithromycin (CEM-101) in Healthy Adult Subjects

The steady-state concentrations of solithromycin in plasma were compared with concomitant concentrations in epithelial lining fluid (ELF) and alveolar macrophages (AM) obtained from intrapulmonary samples during bronchoscopy and bronchoalveolar lavage (BAL) in 30 healthy adult subjects. Subjects rec...

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Detalhes bibliográficos
Main Authors: Rodvold, Keith A., Gotfried, Mark H., Still, J. Gordon, Clark, Kay, Fernandes, Prabhavathi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457395/
https://ncbi.nlm.nih.gov/pubmed/22802254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00766-12
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