Comparison of Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Solithromycin (CEM-101) in Healthy Adult Subjects

The steady-state concentrations of solithromycin in plasma were compared with concomitant concentrations in epithelial lining fluid (ELF) and alveolar macrophages (AM) obtained from intrapulmonary samples during bronchoscopy and bronchoalveolar lavage (BAL) in 30 healthy adult subjects. Subjects rec...

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Main Authors: Rodvold, Keith A., Gotfried, Mark H., Still, J. Gordon, Clark, Kay, Fernandes, Prabhavathi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457395/
https://ncbi.nlm.nih.gov/pubmed/22802254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00766-12
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