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Mechanism of Action of the Arylomycin Antibiotics and Effects of Signal Peptidase I Inhibition

Clinically approved antibiotics inhibit only a small number of conserved pathways that are essential for bacterial viability, and the physiological effects of inhibiting these pathways have been studied in great detail. Likewise, characterizing the effects of candidate antibiotics that function via...

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Detalhes bibliográficos
Main Authors: Smith, Peter A., Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457390/
https://ncbi.nlm.nih.gov/pubmed/22802255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00785-12
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