Origins of Yersinia pestis Sensitivity to the Arylomycin Antibiotics and the Inhibition of Type I Signal Peptidase

Yersinia pestis is the etiologic agent of the plague. Reports of Y. pestis strains that are resistant to each of the currently approved first-line and prophylactic treatments point to the urgent need to develop novel antibiotics with activity against the pathogen. We previously reported that Y. pest...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Steed, Danielle B., Liu, Jian, Wasbrough, Elizabeth, Miller, Lynda, Halasohoris, Stephanie, Miller, Jeremy, Somerville, Brandon, Hershfield, Jeremy R., Romesberg, Floyd E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2015
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468718/
https://ncbi.nlm.nih.gov/pubmed/25896690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00181-15
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