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Myxobacterium-Produced Antibiotic TA (Myxovirescin) Inhibits Type II Signal Peptidase
Antibiotic TA is a macrocyclic secondary metabolite produced by myxobacteria that has broad-spectrum bactericidal activity. The structure of TA is unique, and its molecular target is unknown. Here, we sought to elucidate TA's mode of action (MOA) through two parallel genetic approaches. First,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318312/ https://ncbi.nlm.nih.gov/pubmed/22232277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06148-11 |
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