Inhibition of Protein Secretion in Escherichia coli and Sub-MIC Effects of Arylomycin Antibiotics

At sufficient concentrations, antibiotics effectively eradicate many bacterial infections. However, during therapy, bacteria are unavoidably exposed to lower antibiotic concentrations, and sub-MIC exposure can result in a wide variety of other effects, including the induction of virulence, which can...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Walsh, Shawn I., Peters, David S., Smith, Peter A., Craney, Arryn, Dix, Melissa M., Cravatt, Benjamin F., Romesberg, Floyd E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355593/
https://ncbi.nlm.nih.gov/pubmed/30420476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01253-18
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