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Not just an antibiotic target: exploring the role of type I signal peptidase in bacterial virulence

The looming antibiotic crisis has prompted the development of new strategies towards fighting infection. Traditional antibiotics target bacterial processes essential for viability, whereas proposed antivirulence approaches rely on the inhibition of factors that are required only for the initiation a...

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Detalles Bibliográficos
Publicado en:Bioorg Med Chem
Main Authors: Walsh, Shawn, Craney, Arryn, Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279723/
https://ncbi.nlm.nih.gov/pubmed/27769673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.09.048
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