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Antiviral Drug Resistance and the Need for Development of New HIV-1 Reverse Transcriptase Inhibitors

Highly active antiretroviral therapy (HAART) consists of a combination of drugs to achieve maximal virological response and reduce the potential for the emergence of antiviral resistance. Despite being the first antivirals described to be effective against HIV, reverse transcriptase inhibitors remai...

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Bibliographic Details
Main Authors: Asahchop, Eugene L., Wainberg, Mark A., Sloan, Richard D., Tremblay, Cécile L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457356/
https://ncbi.nlm.nih.gov/pubmed/22733071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00591-12
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