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Dynamic SUMOylation Is Linked to the Activity Cycles of Androgen Receptor in the Cell Nucleus
Despite of the progress in the molecular etiology of prostate cancer, the androgen receptor (AR) remains the major druggable target for the advanced disease. In addition to hormonal ligands, AR activity is regulated by posttranslational modifications. Here, we show that androgen induces SUMO-2 and S...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457344/ https://ncbi.nlm.nih.gov/pubmed/22890844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00753-12 |
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