Nuclear Mobility and Activity of FOXA1 with Androgen Receptor Are Regulated by SUMOylation

Forkhead box (FOX) protein A1 has been dubbed a pioneer transcription factor because it binds target sites in DNA, thereby displacing nucleosomes to loosen chromatin and facilitating steroid receptor DNA binding nearby. FOXA1 is an important regulator of prostate development, collaborating with andr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Endocrinol
Prif Awduron: Sutinen, Päivi, Rahkama, Vesa, Rytinki, Miia, Palvimo, Jorma J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5414787/
https://ncbi.nlm.nih.gov/pubmed/25127374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1035
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