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Transmembrane Protein Aptamers That Inhibit CCR5 Expression and HIV Coreceptor Function
We have exploited the ability of transmembrane domains to engage in highly specific protein-protein interactions to construct a new class of small proteins that inhibit HIV infection. By screening a library encoding hundreds of thousands of artificial transmembrane proteins with randomized transmemb...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457321/ https://ncbi.nlm.nih.gov/pubmed/22811524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00910-12 |
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