CCR2-64I Polymorphism Is Not Associated with Altered CCR5 Expression or Coreceptor Function

A polymorphism in the gene encoding CCR2 is associated with a delay in progression to AIDS in human immunodeficiency virus (HIV)-infected individuals. The polymorphism, CCR2-64I, changes valine 64 of CCR2 to isoleucine. However, it is not clear whether the effect on AIDS progression results from the...

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Main Authors: Mariani, Roberto, Wong, Sally, Mulder, Lubbertus C. F., Wilkinson, David A., Reinhart, Amy L., LaRosa, Gregory, Nibbs, Robert, O’Brien, Thomas R., Michael, Nelson L., Connor, Ruth I., Macdonald, Marcy, Busch, Michael, Koup, Richard A., Landau, Nathaniel R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104492/
https://ncbi.nlm.nih.gov/pubmed/9971830
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