CCR2-64I Polymorphism Is Not Associated with Altered CCR5 Expression or Coreceptor Function

A polymorphism in the gene encoding CCR2 is associated with a delay in progression to AIDS in human immunodeficiency virus (HIV)-infected individuals. The polymorphism, CCR2-64I, changes valine 64 of CCR2 to isoleucine. However, it is not clear whether the effect on AIDS progression results from the...

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Détails bibliographiques
Auteurs principaux: Mariani, Roberto, Wong, Sally, Mulder, Lubbertus C. F., Wilkinson, David A., Reinhart, Amy L., LaRosa, Gregory, Nibbs, Robert, O’Brien, Thomas R., Michael, Nelson L., Connor, Ruth I., Macdonald, Marcy, Busch, Michael, Koup, Richard A., Landau, Nathaniel R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC104492/
https://ncbi.nlm.nih.gov/pubmed/9971830
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