Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates

Microglia are the main human immunodeficiency virus (HIV) reservoir in the central nervous system and most likely play a major role in the development of HIV dementia (HIVD). To characterize human adult microglial chemokine receptors, we analyzed the expression and calcium signaling of CCR5, CCR3, a...

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Main Authors: Albright, Andrew V., Shieh, Joseph T. C., Itoh, Takayuki, Lee, Benhur, Pleasure, David, O’Connor, Michael J., Doms, Robert W., González-Scarano, Francisco
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC103824/
https://ncbi.nlm.nih.gov/pubmed/9847323
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